Methodological Reviewer: Jason Park, MEd, MD, FRCSC, FACS, Department of Surgery, University of Manitoba
Clinical Reviewer: Charles Vollmer, Jr, MD and Fabio Casciani, MD, Department of Surgery, University of Pennsylvania Perelman School of Medicine
Clinical Reviewer: Peter Kim, MD, MSc, FRCSC, FACS, Department of Surgery, University of British Columbia
Ueschel, J. D, Goldsmith C.H, Tandan V.R. et al; for the Evidence-Based Surgery Working Group. Users’ guide to evidence-based surgery: how to use an article evaluating surgical interventions. CJS 2001; 44(2):95-100
Guyatt G.H, Sackett D.L, Cook D.J; for the Evidence-Based Surgery Working Group. User’s Guides to Medical Literature: II.How to Use an Article About Therapy or Prevention A. Are the Results of the Study Valid? JAMA 1993; 270(21):2598-2601
Guyatt G.H, Sackett D.L, Cook D.J; for the Evidence-Based Surgery Working Group. User’s Guides to Medical Literature: II.How to Use an Article About Therapy or Prevention B. What Were the Results and Will They Help Me in Caring for My Patients? 1994;271(1):59-63
Please read the above articles and be prepared to discuss the following:
- Was patient assignment randomized, and the randomization process “concealed”?
- Were all patients who entered the trial accounted for?
- Was follow-up adequate? Were patients analyzed according to the “intention to treat” principle?
- Were study personnel “blinded” to treatment?
- Were the patient groups similar before treatment?
- Apart from the experimental intervention, were the groups treated equally?
- How large was the treatment effect?
- How precise was the estimate of the treatment effect?
- Were the study patients similar to my patients?
- Were the measured outcomes clinically relevant?
- Are my surgical skills similar to those of the study surgeons?
- Does the evidence support the conclusions?