Munck F, Clausen E.W., Balslev E, Kroman N, Tvedskov T.F., Holm-Rasmussen E.V. Multicentre study of the risk of invasive cancer and use of sentinel node biopsy in women with a preoperative diagnosis of ductal carcinoma in situ. BJS 2020; 107: 96-102.
Methodological Reviewer: Angel Arnaout, MD MSc FRCSC FACS, Breast Surgical Oncologist, General Surgery, Ottawa Hospital, University of Ottawa
Clinical Reviewer: Heather Neuman, MD MS FACS, Associate Professor, Division of Surgical Oncology, University of Wisconsin School of Medicine and Public Health
Clinical Reviewer: Sarah Knowles, MD Breast Surgical Oncologist and General Surgeon, St. Joseph’s Health Care, Western University
Jaeschke R, Guyatt G, Sackett D. L. Users’ guides to the medical literature: III. How to Use an Article About a Diagnostic Test. B. What Are the Results and Will They Help Me in Caring for My Patients? JAMA; 1994; 271(5):703
Please read the above articles and be prepared to discuss the following:
- What is the clinical question being addressed?
- What is the rationale for the study?
- What is the study design?
- Was the assignment of patients to treatment randomized?
- Were all the patients who entered into the trial properly accounted for and attributed at its conclusion?
- Did the sample include an appropriate spectrum of patients and were groups similar at baseline?
- Were the methods for performing the test described in sufficient detail to permit replication?
- Aside from the experimental intervention, were the groups treated equally?
- Were all clinically important outcomes considered?
- How large and precise was the treatment effect?
- Are the likely benefits worth the potential harm and costs?
- Will the reproducibility of the test result and its interpretations be satisfactory in my setting?
- State the conclusion. Have the authors addressed the clinical question posed?
- Does the evidence support the conclusion?