Overview
Start Module Featured Article
Darouiche RO, Wall MJ, Itani KMF, et al. Chlorhexidine-alcohol versus povidone-iodine for surgical site antisepsis. New Eng J Med 2010;362(1):18-26
Expert Reviews
Methodological Reviewer
Elijah Dixon MD, BSc, MSc, FRCSC, FACS Department of Surgery, University of Calgary
Clinical Reviewer
William Cheadle MD, Department of Surgery, University of LouisvilleSupplementary Articles
Guyatt GH, Sackett DL, Cook DJ, for the Evidence Based Medicine Working Group. Users’ Guides to the Medical Literature. II. How to Use an Article about Therapy or Prevention. JAMA 1993 Dec 1; 270(21): 2598-2601
Guyatt GH, Sackett DL, Cook DJ, for the Evidence Based Medicine Working Group. Users’ Guides to the Medical Literature. II. How to Use an Article about Therapy or Prevention. JAMA 1994 Jan 5; 271(1): 59-63
Questions
- What is the clinical question being addressed?
- Was the assignment of patients to treatment randomized?
- Were all patients who entered the trial properly accounted for and attributed at its conclusions?
- Were patients, their clinicians and study personnel “blind” to treatment?
- Were the groups similar at the start of the trial?
- Aside from the experimental intervention, were the groups treated equally?
- How large and precise was the treatment effect?
- Were all clinically important outcomes considered?
- State the conclusion. Have the authors addressed the clinical question posed?
- Does the evidence support the conclusion?