Predictive Value of C-reactive Protein

Overview

Featured Article


Warshkow R, Beutner U, Steffen T, et al. Safe and early discharge after colorectal surgery due to C-Reactive protein. Ann Surg 2012;256:245-250

Expert Reviews


Methodological Reviewer: Prosanto Chaudhury MD, MSc, FRCSC, FACS, Department of Surgery, McGill University
Clinical Reviewer: Marc Jeschke, MD PhD FACS FCCM FRCS(C), Department of Surgery, University of Toronto
Clinical Reviewer: John RT Monson MD, FRCS, FACS, Department of Surgery, University of Rochester Medical Centre

Supplementary Article


Stroup DF, Berlin JA, Morton SC, et al. Meta-analysis of observational studies in epidemiology. JAMA 2000;283(15):2008-2012

Questions


Please read the above articles and be prepared to discuss the following:

  1. What is the clinical question being addressed?
  2. Did the review explicitly address a sensible clinical question?
  3. Was the search for relevant studies detailed and exhaustive?
  4. Were the primary studies of high methodologic quality?
  5. Were the assessments of studies reproducible?
  6. Were the results similar from study to study?
  7. What are the overall results of the review?
  8. Were the clinically important outcomes considered?
  9. State the conclusion. Have the authors addressed the clinical question posed?
  10. Does the evidence support the conclusion?