Early Cholecystectomy for Cholecystitis

Overview

Featured Article


Roulin D, Saadi A, Di Mare L, et al. Early versus delayed cholecystectomy for acute cholecystitis, are the 72 hours still the rule? A randomized trial. Ann Surg 2016;264(5):717-722annuals of surgery pack

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Expert Reviews


Methodological Reviewer: Lillian Kao MD, MS FACS, Department of Surgery, University of Texas HSC
Clinical Reviewer: Chad Ball MD, MSc, FRCSC, FACS, Department of Surgery, University of Calgary
Clinical Reviewer: Prosanto Chaudhury MD, MSc, FRCSC, FACS
Department of Surgery, McGill University

Supplementary Articles


Guyatt GH, Sackett DL, Cook DJ, for the Evidence Based Medicine Working Group. Users’ Guides to the Medical Literature. II. How to Use an Article about Therapy or Prevention (A). JAMA 1993 Dec 1; 270(21): 2598-2601

Guyatt GH, Sackett DL, Cook DJ, for the Evidence Based Medicine Working Group. Users’ Guides to the Medical Literature. II. How to Use an Article about Therapy or Prevention (B). JAMA 1994 Jan 5; 271(1): 59-63

Questions


Please read the above articles and be prepared to discuss the following:

  1. What is the clinical question being addressed?
  2. Was the assignment of patients to treatment randomized and concealed?
  3. Were all patients who entered the trial properly accounted for and attributed for at is conclusion?
  4. Were patients, their clinicians and study personnel “blind” to treatment?
  5. Were the groups similar at the start of the trial?
  6. Aside from the experimental intervention, were the groups treated equally?
  7. How large and precise was the treatment effect?
  8. Can the results be applied to my patient care?
  9. Were all clinically important outcomes considered?
  10. Are the likely treatment benefits worth the potential harm and costs?
  11. State the conclusion. Have the authors addressed the clinical question posed?
  12. Does the evidence support the conclusion?