Featured Article
State LL, Liu YL, Syngal S, et al. Nut, Corn and Popcorn Consumption and the Incidence of Diverticular disease. JAMA 2008;300(8):907-14
Expert Reviews:
Supplementary Articles
Mitchell L, Walter S, Lee H, Haines T, Holbrook A, Moyer V, for the Evidence-Based Medicine Working Group. Users’ Guides to the Medical Literature. IV. How to Use an Article about Harm. JAMA 1994; 271(20): 1615-1619
Questions
Please read the provided articles and be prepared to discuss the following:
1. What is the clinical question being addressed?
2. Were there clearly identified comparison groups that were similar with respect to important determinants of outcome other than the one of interest?
3. Were the exposures and outcomes measured in the same way in the groups being compared?
4. Was follow-up sufficiently long and complete?
5. Is the temporal relationship correct?
6. Is there a dose-response gradient?
7. How strong is the association between exposure and outcome and how precise is the estimate of risk?
8. Are the results genealizable?
9. What is the magnitude of the risk?
10. Should I attempt to stop the exposure? Or should I encourage “the exposure”?
11. State the conclusion. Have the authors addressed the clinical question posed?
12. Does the evidence support the conclusion?