Holcomb JB, del Junco DJ, Fox EE, et al for the PROMMTT Study Group. The prospective, observational multicenter major trauma transfusion (PROMMTT) study. Arch Surg 2012;15:1-10. doi: 10.1001/2013.jamasurg.387
Methodological Reviewer: Andy Kirkpatrick, CD, MD, MHSc, FRCSC, FACS, Departments of Surgery and Critical Care Medicine, University of Calgary and Foothills Medical Centre
Clinical Reviewer: Chad G. Ball, MD, MSc, FRCSC, FACS, Department of Surgery, University of Calgary and Foothills Medical Centre
Clinical Reviewer: K. Pavenski, MD, FRCPC, Department of Laboratory Medicine and Pathobiology, University of Toronto
Clinical Reviewer:Juan C Duchesne MD, FACS, FCCM, FCCP, Department of Surgery, Tulane University
Hansebout RR, Cornacchi SD, Haines T, et al; for the Evidence-Based Surgery Working Group. Users’ guide to the surgical literature. How to use an article about prognosis. Can J Surg 2009;52(4):328-36
- What is the clinical question being addressed?
- Was there a representative and well-defined sample of patients at a similar point in the course of the disease?
- Was follow-up sufficiently long and complete?
- Were objective and unbiased outcomes criteria used?
- Was there adjustment for important prognostic factor?
- How large is the likelihood of the outcome event(s) in a specified period of timeHow precise are the estimates of likelihood?
- Will the results help me in caring for my patients?
- Will the results lead directly to selecting or avoiding therapy?
- Are the results useful for reassuring or counseling patients?
- State the conclusion. Have the authors addressed the clinical question posed?
- Does the evidence support the conclusion?